A Transgenic Heavy Chain IgG Mouse Platform as a Source of High Affinity Fully Human Single-Domain Antibodies for Therapeutic Applications

The antibody repertoires of transgenic mice expressing human heavy chain only antibodies (HCAbs) can be retrieved from immune cells after antigen challenge. Compared with genetically modified rodents expressing conventional human antibodies (tetramers consisting of two heavy chains paired with two light chains), there is no chain pairing problem, since each antibody consists of a heavy…

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Yeast identification by sequencing, biochemical kits, MALDI-TOF MS and rep-PCR DNA fingerprinting.

No research has comprehensively evaluated the efficiency of 28S nrDNA and ITS sequencing, industrial biochemical check kits, MALDI-TOF MS platforms, and the rising rep-PCR DNA fingerprinting know-how utilizing a cohort of yeast strains collected from a medical microbiology laboratory. On this research, utilizing 71 clinically vital yeast isolates (excluding Candida albicans) collected from a single…

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pureexo exosome isolation kit

pureexo exosome isolation kit

Further Data Product Tags Cat. No. BL-P100 PureExo Cell Producer 101Bio Key Options Straightforward to make use of: No ultra-centrifugation (< 2 hours) 10 fold greater yield (vs. different kits and ultracentrifuge) Save value (vs. antibodies-beads methodology) Isolate Pure exosome (>95%) Intact exosome (good morphology) Use as little as 2 mL cell media to realize…

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mybiosource

Cytochrome C ELISA Kits from MyBioSource

The ELISA (enzyme-linked immunosorbent assay) is a widely used application for detecting and quantifying proteins and antigens from various samples. Target-specific ELISA kits are available from a variety of manufacturers and can help streamline your immunodetection experiments. Listed are ELISA Kits for the detection of cytochrome C, an alias name of cytochrome c, somatic. The…

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computablegenomix

epigentek methylflash methylated dna quantification kit

Product Overview The MethylFlash Methylated DNA Quantification Package (Fluorometric) is a whole set of optimized buffers and reagents to fluorometrically quantify international DNA methylation by particularly measuring ranges of 5-methylcytosine (5-mC) in a microplate-based format. In comparison with LUMA or LINE-1, Alu, and LTR-based assays, MethylFlash™ expertise straight quantifies precise international DNA methylation. This equipment can also be particularly optimized for…

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Ultra Rainbow

SPHEROT Ultra Rainbow Fluorescent Particles

New movement cytometers, with fluorescent channels from the UV to Far Pink, and corresponding fluorescent conjugates at the moment are accessible. In consequence, we now have developed the Extremely Rainbow Fluorescent Particles with enhanced UV and Far Pink fluorescence depth. The Extremely Rainbow Fluorescent Particles include a single peak and are designed for checking the…

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computablegenomix

Direct RT-qPCR assay for SARS-CoV-2 variants of concern (Alpha, B.1.1.7 and Beta, B.1.351) detection and quantification in wastewater

Lower than a 12 months following the Extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, variants of concern have emerged within the type of variant Alpha (B.1.1.7, the British variant) and Beta (B.1.351, the South Africa variant). Resulting from their excessive infectivity and morbidity, it has grow to be clear that it’s essential to rapidly…

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computablegenomix

Comparison of SARS-CoV-2 Detection by Rapid Antigen and by Three Commercial RT-qPCR Tests: A Study from Martin University Hospital in Slovakia

The worldwide pandemic of coronavirus illness 2019 (COVID-19) brought on by the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is having an incredible affect on the worldwide financial system, well being care programs and the lives of virtually all folks on this planet. The Central European nation of Slovakia reached one of many highest day…

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computablegenomix

Comparison between Whatman FTA Elute Cards and Conventional Swab for the Detection of Pathogenic Enteric Bacteria Using an RT-qPCR Assay

The emergence of outbreaks of foodborne sickness is carefully related to meals contamination attributable to varied enteric pathogens, resembling Escherichia coli O157:H7, Listeria monocytogenes, Salmonella enterica serovar Enteritidis, and Staphylococcus aureus. The management of enteric pathogens poses a problem attributable to the truth that these pathogens can persist for an extended time frame within the surroundings. The fast detection of pathogenic…

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computablegenomix

A novel multiplex qPCR method for assessing the comparative lengths of telomeres

Background: The comparative size of telomeres is taken into account to be associated to illnesses similar to most cancers, growing old, and cardiovascular illnesses. qPCR is at the moment one of many fundamental strategies for detecting telomere size. Nevertheless, because of the distinctive sequence of telomeres (extremely repetitive six-base sequence), it’s troublesome to design primers and…

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