E. coli exoribonuclease of RNase R

Biovision rnase-r

APPLICATIONS:
• Enriching circRNAs in natural samples
• Identification of intronic lariat sequences
• Identification of exonic circRNAs
• Studying varied splicing
• Manufacturing of artificial spherical RNAs

 

DESCRIPTION:

RNase R is an E. coli exoribonuclease which shows 3’-to-5’ exonuclease train, successfully digesting virtually all linear RNA species. This enzyme does not digest spherical, lariat, or double stranded RNA with temporary 3’ overhangs (decrease than sevennucleotides). As such, this enzyme is ideally suited to the study of lariat RNA produced by typical splicing, along with circRNAs which come up by way of back-splicing.

EZYME UNIT DEFINITION: One unit is printed as the amount of RNase R that converts 1
µg of poly(A) into acid soluble nucleotides in 10 minutes at 37°C. ENZYME STORAGE BUFFER: 50 mM Tris-HCl (pH 7.5), 100mM NaCl, 0.1 mM EDTA, 1 mM DTT, and 50% (v/v) Glycerol 10X RNase R REACTION BUFFER COMPONENTS: 200 mM Tris-HCl, 1 M KCl, 1 mM, MgCl2, pH 7.5.

STORAGE CONDITIONS: Retailer at -20°C.

Stay away from repeated freeze-thaw cycles of all components to retain most effectivity. All components
are regular for one 12 months from the date of transport when saved and handled appropriately.

 

Biovision rnase-r
Biovision rnase-r
Cat # +DimensionM1228-500
Dimension500 U
HighlightsRNase R is an E. coli exoribonuclease which shows 3’-to-5’ exonuclease train, successfully digesting virtually all linear RNA species.
Storage Conditions-20°C
Supply ConditionsGel Pack
USAGEFor Evaluation Use Solely! Not For Use in Individuals.

 

 

RELATED PRODUCTS:

• RNase A (Cat# M1227-25)
• RNaseOFF ribonuclease Inhibitor (Cat# M1238-4000)
• DNase, E.coli DNA Ligase (Cat# M1217-100)
• Hyperlink-FAST 5 Minutes DNA Ligation Package deal (Cat# Okay902-50)
• New T4 DNA Ligase (Cat# M1247-200)
• T4 DNA Ligase (5 u/μl) (Cat# 9101-250)
• T4 RNA Ligase 1 (ssRNA Ligase) (Cat# M1218-100)
• T4 RNA Ligase 2 (dsRNA Ligase) (Cat# M1219-100)

 

RNAse
E16FXP0211R-400 400 μl
EUR 20
Description: Available in various conjugation types.
RNAse
E16FXP0211R-800 800 μl
EUR 26.67
Description: Available in various conjugation types.
RNase A
abx098139-1ml 1 ml
EUR 260.4
PI / RNAse
abx290029-200tests 200 tests
EUR 326.4
PI/RNAse
PI/RNASE 200 test
EUR 208.2
RNase A
M1227-25 each
EUR 294
RNase A
RN103-001 300mg
EUR 3138
RNase A
RB0473 500mg
EUR 219.73
RNase A
IB47163 50ul
EUR 20.72
Description: (FOR HI-SPEED PLASMID) [FR}
RNase H
RK20535 250U
EUR 88
RNase FREE, 250ml Bottle Removes RNase & DNAse
10-172 1 Bottle/Unit
EUR 269
Rnase (90–105)
5-01885 4 x 1mg Ask for price
Rnase A, 250mg
R9001-250mg each
EUR 337.2
RNase Inhibitor
EQ010 1000U
EUR 33.5
RNase FREE, 1 Liter Bottle Removes RNase & DNAse
10-173 1 Bottle/Unit
EUR 337
RNase FREE, 4 Liter Bottle Removes RNase & DNAse
10-456 1 Bottle/Unit
EUR 403
RNase FREE, 475ml Spray Bottle Removes RNase & DNAse
10-228 1 Spray Bottle/Unit
EUR 300
Rnase A, 1g
R9001-1g each
EUR 986.4
Rnase A, 1g
R9001 1g
EUR 667.9
RNase A (MBG)
409-050 50 mg
EUR 87.6
RNase A (MBG)
409-250 250 mg
EUR 231.6
RNase L Antibody / Rnasel
RQ6435 100 ug
EUR 356.15
Description: RNase L is an enzyme that in humans is encoded by the RNASEL gene. This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
RNase III, E.coli
M1226-100 each
EUR 268.8
RNase L Peptide
46-735P 0.1 mg
EUR 405.6
Description: ABCE1 / RNase L Peptide
RNase T2 Antibody
abx237324-100ug 100 ug
EUR 610.8
RNase 1 Antibody
20-abx141499
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul
RNase 13 Antibody
20-abx141582
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul
RNAse H2A Peptide
4979P 0.05 mg
EUR 197.7
Description: (IN) RNAse H2A peptide
RNase A Solution
G118 1.0 ml; 10 mg/ml
EUR 122.4
RNase H1 Antibody
DF12084 100ul
EUR 280
Description: Human,Mouse,Rat
RNase T2 antibody
E39-07324 100ug/100ul
EUR 225
Description: Available in various conjugation types.
RNase H1 Antibody
DF12084-100ul 100ul
EUR 280
RNase H1 Antibody
DF12084-200ul 200ul
EUR 350
RNase T2 antibody
CAF50297-100ug 100ug
EUR 338
DNase (RNase-free)
abx098138-1500U 1500 U
EUR 543.6
RNase-Free water
abx098145-25ml 25 ml
EUR 210
RNAse H2A Antibody
24819-100ul 100ul
EUR 468
RNAse H2A Antibody
4979-002mg 0.02 mg
EUR 206.18
Description: RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
RNAse H2A Antibody
4979-01mg 0.1 mg
EUR 523.7
Description: RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
Rnase A, Pancreatic
abx082443-25mg 25 mg
EUR 226.8
Thermostable RNAse H
M1224-100 each
EUR 385.2
RNase A (100 mg/ml)
DE111-01 500 μl
EUR 23.2